Link between the albumin-corrected anion gap and 28 day all‑cause mortality among patients with sepsis complicated with chronic heart failure: A retrospective analysis using the eICU Collaborative Research Database.

ABSTRACT:

Background

These two conditions, namely metabolic acidosis and hypoproteinemia, are prevalently observed in patients within intensive care units (ICU), particularly those with sepsis complicated with chronic heart failure. Nevertheless, the impact of the Albumin-Corrected Anion Gap (ACAG), an indicator reflecting the above conditions, on such patient mortality requires further investigation. This retrospective cohort study analyzed the significance of ACAG levels in forecasting 28-day all-cause mortality among these patients admitted to ICU.

Methods

This was observational cohort study on eICU Collaborative Research Database (eICU-CRD) that included in participants with sepsis complicated with chronic heart failure. In the study, we applied several methods such as multivariat

SUBMITTER: Zhang C 

PROVIDER: S-EPMC12707619 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature