Comparing Two Oral Immunotherapy Strategies for Sesame Allergy: Baked Goods with Sesame Paste versus Crushed Sesame Seeds.

ABSTRACT:

Introduction

Sesame allergy is reported to be a major trigger of food-induced anaphylaxis and is associated with increased risk of accidental exposure. This study aimed to assess the efficacy and safety of a modified sesame desensitization protocol in children in real-world clinical practice.

Methods

Children with a positive skin prick test and a history consistent with an IgE-mediated allergy to sesame presenting at the Allergy Clinic of the Montreal Children's Hospital were recruited. After parents provided informed consent, an initial dose of sesame protein was introduced in the form of baked sesame paste (tahini) muffin or raw sesame seeds under physician supervision. An initial dose of 1/4 teaspoon (5 mg sesame protein) was given to the baked group, reaching a maintenan

SUBMITTER: Khalaf R 

PROVIDER: S-EPMC12707878 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature