Effectiveness of the Crohn's Disease Exclusion Diet for the Treatment of Crohn's Disease in the Older-Adult Population: Real-World Experience.

ABSTRACT:

Introduction: The management of Crohn's disease (CD) in older-adult patients is challenging due to age-related immune decline, comorbidities, and the excessive risk of adverse effects from pharmacological treatments. The Crohn's Disease Exclusion Diet (CDED) has shown promise in treating younger populations, but its effectiveness in older-adults remains understudied. This study aimed to evaluate the CDED effectiveness in older-adults with CD.

Methods

A single-center retrospective cohort study, including patients over 60 years old with CD who initiated CDED between 2018 and 2024. Patients were categorized based on baseline disease clinical activity using the Harvey Bradshaw Index (HBI). Clinical and biochemical outcomes (fecal calprotectin [FCAL] and C-reactive protein) were asses

SUBMITTER: Meir Y 

PROVIDER: S-EPMC12707889 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature