Extensive Alopecia Mucinosa and Response to Brentuximab Vedotin: A Case Report.

ABSTRACT:

Introduction

Follicular mucinosis (FM) is characterized by mucin deposition within hair follicles and sebaceous glands, sometimes causing irreversible alopecia. In adults, it is often secondary to cutaneous T-cell lymphoma (CTCL), particularly the folliculotropic mycosis fungoides (FMF) variant. Extensive scalp involvement is rare and may mimic inflammatory or infectious disorders, delaying diagnosis.

Case presentation

A 64-year-old woman presented with progressive diffuse alopecia, suppurative scalp nodules, comedones, leonine facies, and multiple erythematous plaques. Initial biopsies elsewhere suggested tuberculoid leprosy, and multidrug therapy produced no improvement. Trichoscopy showed nonspecific signs suggestive of dissecting cellulitis, but histopathology revealed m

SUBMITTER: Montoya C 

PROVIDER: S-EPMC12707941 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature