Does Body Mass Index Impact the Outcomes of Peritoneal Dialysis Patients? A Systematic Review and Meta-Analysis of Non-Randomized Trials.

ABSTRACT:

Introduction

Body mass index (BMI) is a risk factor for adverse consequences in chronic kidney disease patients. However, its impact on patients undergoing peritoneal dialysis (PD) remains uncertain. We conducted a comprehensive systematic review and meta-analysis to assess the impact of baseline BMI on PD outcomes.

Methods

All studies reporting outcomes of PD patients based on WHO-defined BMI groups were identified from PubMed, Embase, Scopus, and Cochrane Library databases up to March 30, 2025. Mortality, peritonitis rate, transfer to hemodialysis (HD), and technique failure were assessed.

Results

Eighteen studies were included. Meta-analysis of crude data showed a significantly increased risk of mortality in obese patients, while meta-analysis of adjusted data show

SUBMITTER: Chen X 

PROVIDER: S-EPMC12707942 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature