Comparative Genomics of the Testacea Group of Drosophila Reveals Introgression and Variation in Chromosome Size and Structure.

ABSTRACT: Comparative genomic analyses among closely related species provide an opportunity to assess their evolutionary history. The relatedness between species can depend on a variety of factors, including reproductive isolation, introgression, and incomplete lineage sorting, and this can impact divergence across the genome. Here, we use a combination of long- and short-read sequencing and HI-C scaffolding to assemble genomes for each of the four species in the testacea species group of Drosophila, including D. testacea, D. orientacea, D. neotestacea, and D. putrida, and its outgroup, D. bizonata. First, among species, we find many structural rearrangements across the genome as well as a large size difference in the dot chromosome that we infer is due to the expansion of repetitive elements. Secon

SUBMITTER: Erlenbach T 

PROVIDER: S-EPMC12708344 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature