Adverse events in meningioma surgery classified using the therapy-disability-neurology (TDN) grading system.

ABSTRACT:

Purpose

Meningiomas are common, mostly benign, and often asymptomatic. Minimizing surgical adverse events (AE) is essential to maintain a favorable risk-benefit balance. Traditional AE grading systems often failed to account for disabling complications like neurologic deficits, which led to the development of the multidimensional therapy-disability-neurology grade (TDN). This study evaluates risk factors and consequences of AE in meningioma patients using TDN.

Methods

Pre- and perioperative factors associated with the occurrence and severity of AE at discharge and follow-up were retrospectively identified in a monocentric cohort of consecutive patients undergoing surgery between 2013 and 2022. Significant variables of the univariable analysis were consequently tested in a mu

SUBMITTER: Leistner T 

PROVIDER: S-EPMC12708695 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature