Evidence of cancer: a systematic review of metabolomics in extracellular vesicles for cancer biomarker detection.

ABSTRACT:

Background

The early detection of cancer remains a critical challenge in clinical oncology, with significant implications for patient survival rates and treatment outcomes. Research focus has shifted to developing minimally invasive diagnostic approaches for cancer detection and prognosis, such as metabolomic analysis of biological fluids and tumour-derived components, including extracellular vesicles (EVs). EVs carry molecular cargo, including metabolites, that reflect the pathophysiological state of their cell of origin. Analysis and characterisation of these metabolites may offer novel insights into cancer biology and facilitate the identification of potential biomarkers.

Aim of review

This review systematically examines existing literature on the metabolomic analysis of

SUBMITTER: Mayhew M 

PROVIDER: S-EPMC12708750 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature