Outcomes of septic shock from urinary and non-urinary sources in nonagenarians and centenarians admitted to intensive care units.

ABSTRACT: Although sepsis-related mortality has declined with advances in care, the incidence of septic shock is rising by 1-8% annually. As life expectancy increases, the ≥ 90-year-old population is projected to reach 10 million in the U.S. by 2050, highlighting septic shock as a growing public health burden. Despite urinary tract infections being a common cause, non-urinary sources may carry higher mortality. However, outcome data in nonagenarians and centenarians are limited. This study compares outcomes by infection source in ICU patients aged 90 years or older with septic shock. This retrospective study, approved by the Alfred Ethics Committee (No. 253/24), used de-identified data from the ANZICS Adult Patient Database (2010-2023), including nonagenarian and centenarian ICU patients with septic

SUBMITTER: Suh JM 

PROVIDER: S-EPMC12708794 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature