Ex vivo Sealing Performance of a Sutureless Dual-Component Connector for Coronary Bypass.

ABSTRACT: Sutureless coronary connectors may enable minimally invasive bypass surgery, but consistent sealing in human vessels remains a key challenge. This ex vivo study evaluates the hydrostatic performance of a titanium connector that employs a novel sealing principle: tissue-to-metal coaptation enabling stepwise distal anastomosis construction. Thirteen anastomoses were created in porcine and human cadaveric vessels using a standardized three-step deployment protocol. Target sites included internal mammary arteries, saphenous veins, and coronary arteries, selected for suitability for hand-suturing. Sealing was assessed by hydrostatic pressure testing up to 300 mmHg. Key anatomical parameters and procedural outcomes were recorded. Twelve of 13 anastomoses were completed without leakage up to 300

SUBMITTER: Gianoli M 

PROVIDER: S-EPMC12709125 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature