Diagnosis and Management of Functional Pancreatic Neuroendocrine Tumors in Children-A Systematic Review.

ABSTRACT: Background: Functional pancreatic neuroendocrine tumors (FpNETs) are extremely rare in childhood and adolescence, with an incidence of less than 0.1 per million. Since there is currently no systematic review of the literature on FpNETs in children, this study aims to summarize findings from studies focusing on clinical characteristics, diagnostics, treatment modalities, and outcomes. Methods: A systematic review was conducted following the PRISMA guidelines. A literature search was performed using three electronic databases: PubMed, Scopus, and Web of Science. An age filter was used during the search to limit results to childhood and adolescence. There was no limit set in relation to the type and the language of the article. Results: Out of 80,742 records identified, 9

SUBMITTER: Keretic D 

PROVIDER: S-EPMC12709227 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature