Automated EEG Background Analysis and 2-Year Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy.

ABSTRACT:

Importance

Hypoxic-ischemic encephalopathy (HIE) remains an important contributor to neonatal mortality and morbidity despite therapeutic hypothermia. Accurate early prognostication of outcomes is essential for clinical management and risk stratification in future trials.

Objective

To evaluate the feasibility and estimative ability of automated electroencephalographic (EEG) background analysis in projecting neurodevelopmental outcomes in neonates with HIE using the Brain State of the Newborn (BSN) score.

Design, setting, and participants

This cohort study was a secondary analysis of the High-Dose Erythropoietin for Asphyxia and Encephalopathy (HEAL) trial, which enrolled infants born between January 25, 2017, and October 9, 2019, and were followed up at age 2 years (b

SUBMITTER: Cornet MC 

PROVIDER: S-EPMC12709380 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature