Effects of composite yeast culture on the expression of immune-related genes in the splenic tissue of weaned lambs.

ABSTRACT: The objective of this study was to evaluate the effects of dietary supplementation with a composite yeast culture (CYC) on the immune status and splenic gene expression in weaned lambs. Eighteen healthy, male weaned lambs of similar age and body weight were randomly assigned to three groups, including the control group (Con, basal TMR diet), the CYC1 group (TMR supplemented with 40 g/day/lamb of CYC), and CYC2 group (TMR supplemented with 50 g/day/lamb of CYC). The pre-feeding period lasted for 7 days, followed by a 40-day formal experimental period. Upon completion of the experiment, spleens were collected from the three groups of weaned lambs, weighed, and appropriate tissue samples were obtained for histological sectioning, ELISA analysis, RT-qPCR testing, and transcriptome sequencing.

SUBMITTER: Lu Y 

PROVIDER: S-EPMC12709749 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature