Characterization of the gut microbiota in people with different levels of obesity.

ABSTRACT:

Purpose

With the evolution of dietary habits, obesity has emerged as a significant global health issue. Numerous studies have demonstrated a close association between obesity and gut microbiota; however, the specific contribution of gut microbiota to varying degrees of obesity remains inadequately understood. Consequently, this study aims to characterize the gut microbiota of individuals across different obesity severity levels.

Methods

We conducted a comprehensive characterization of the gut microbiome in Chinese obese patients and a healthy control group through the application of 16S rRNA gene sequencing, supplemented by metagenomic sequencing. The study cohort was stratified into five distinct categories based on body mass index (BMI): healthy, overweight, and obesity gr

SUBMITTER: Li E 

PROVIDER: S-EPMC12709931 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature