Associations of Early Life Ambient PM_2.5 Exposure With Asthma Risk in a Cohort of Preterm Infants With Bronchopulmonary Dysplasia.

ABSTRACT:

Objective

To examine whether exposure to fine particulate matter (PM_2.5) during the first year after neonatal intensive care unit (NICU) discharge is associated with asthma by age 5 among infants with bronchopulmonary dysplasia (BPD).

Methods

We conducted a retrospective cohort study of 337 infants with BPD, born between 2010 and 2019, who survived to discharge with clinical follow-up in the Children's Hospital of Philadelphia Care Network through age 5. Daily residential census block group PM_2.5 exposures were estimated using a spatiotemporal machine-learning model and averaged over the first year after NICU discharge. Modified Poisson regression models with robust standard errors quantified associations of PM2.5 with asthma by age 5, adjusting for neo

SUBMITTER: Gomez LF 

PROVIDER: S-EPMC12710147 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature