Relation of changes in PEF and FEV₁ during bronchodilation in children.

ABSTRACT:

Introduction

Asthma diagnosis can be confirmed through the observation of significant bronchodilator response (BDR) measured by peak expiratory flow (PEF) during home monitoring or by forced expiratory volume in one second (FEV₁) with spirometry in a clinical setting.

Aim

To use salbutamol administration after an exercise challenge test in children as a model of bronchodilation to assess how well relative change in PEF reflects improvement in lung function, as defined by increase in FEV₁.

Methods

We retrospectively studied 326 free running exercise challenge tests with spirometry in children 6-16 years old. To assess congruency and differences between relative changes in PEF and FEV₁ during bronchodilation, a regression analysis was pe

SUBMITTER: Csonka LL 

PROVIDER: S-EPMC12710255 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature