Genomic re-evaluation of clinical isolates reveals a structured <i>Streptococcus suis</i> complex.

ABSTRACT: Accurate species-level identification among Streptococcus suis and its close relatives remains challenging due to limited resolution of existing diagnostic tools and incomplete taxonomic frameworks. We investigated 61 isolates from diseased swine and three from cows identified as S. suis by MALDI-TOF MS, but which tested negative by a recN gene-based PCR assay commonly used for species confirmation. Whole-genome sequencing revealed that only four isolates were S. suis sensu stricto, while most others belonged to Streptococcus parasuis, Streptococcus ruminantium, Streptococcus iners, Streptococcus suivaginalis, Streptococcus hepaticus, and several other newly proposed Streptococcus species. Core genome phylogenies consist

SUBMITTER: Li K 

PROVIDER: S-EPMC12710308 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature