Strain matters: host responses reflect symbiont origin in the squid-vibrio symbiosis.

ABSTRACT: Understanding the cause and consequences of bacterial strain variation remains a challenge in the study of symbioses. While the diverse reactions of the host immune system to strain variants have been well studied in pathogenesis, much less is known about how strain variation influences beneficial associations. From the complex vertebrate gut microbiome to the more tractable invertebrate models of symbiosis, the host's cellular and molecular responses to this diversity remain largely a mystery. Here, we explore strain diversity in Vibrio fischeri, the bioluminescent bacterial symbiont of the Hawaiian bobtail squid, Euprymna scolopes. Phylogenetic analyses of the genomes of 62 V. fischeri strains, including 50 light organ-associated and 12 planktonic isolates, re

SUBMITTER: Beilinson V 

PROVIDER: S-EPMC12710313 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature