Comparison of VITEK REVEAL fast antimicrobial susceptibility testing to antibiotic disk diffusion for gram-negative bloodstream infections.

ABSTRACT: The VITEK REVEAL antimicrobial susceptibility testing (AST) system is a fast in vitro diagnostic device that determines the antimicrobial susceptibility profile of gram-negative organisms from positive blood culture after independent organism identification. The objectives of this study were to (i) compare the performance of VITEK REVEAL to disk diffusion (DD) and (ii) evaluate implementation of VITEK REVEAL into a laboratory workflow that employs matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) as the primary method for organism identification. A total of 150 monomicrobial, GN-positive blood cultures were enrolled, of which 47.3% (71/150) contained Escherichia coli, 17.3% (26/150) Klebsiella pneumoniae, and 15.3% (23/150)

SUBMITTER: Bui TI 

PROVIDER: S-EPMC12710352 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature