Maternal Renal Function During Pregnancy and the Early Postpartum Period in Normotensive and Hypertensive Pregnancies.

ABSTRACT:

Aim

We aimed to assess renal function trends during pregnancy and the early postpartum period and establish trimester-specific reference ranges for maternal renal function parameters in Japan, including comparisons with pregnancies complicated by hypertensive disorders of pregnancy (HDP) and preeclampsia.

Methods

This multicenter retrospective study used data collected from 12 primary maternity care units in Japan between 2011 and 2018. Serum creatinine and blood urea nitrogen (BUN) levels were analyzed from early pregnancy to postpartum Day 7 in 17 460 women with uncomplicated term pregnancies (37^0/7-41^6/7 weeks of gestation) and 1460 women with HDP. Additionally, 17 460 non-pregnant women matched for age, body weight, and height were included in the s

SUBMITTER: Ushida T 

PROVIDER: S-EPMC12710551 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature