Clinicopathological characteristics and prognosis analysis of gastrinoma based on the SEER database.

ABSTRACT: Gastrinoma, distinguished by Zollinger-Ellison Syndrome, is a highly unusual neoplasm. However, understanding of its clinicopathological characteristics and survival at the population level is inadequate. This study aimed to examine the clinicopathological features and survival of gastrinoma patients utilizing the Surveillance, Epidemiology, and End Results (SEER) database. Patients diagnosed with gastrinoma from 2000 to 2020 were included in the study. Multiple imputation was used to handle missing data. Chi-square test was employed to analyze the clinicopathological features. The Kaplan-Meier method and Cox proportional hazards models were utilized to evaluate overall survival (OS) and cancer-specific survival (CSS). A total of 160 patients participated in the study. The incidence rate r

SUBMITTER: Qiu C 

PROVIDER: S-EPMC12711040 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature