Impact of lymph node dissection on overall survival and cancer-specific survival in elderly patients with early-stage non-small cell lung cancer: a SEER database analysis.

ABSTRACT: Aim: The aim of the study is to understand the impact of lymph node dissection (LND) on overall survival (OS) and cancer-specific survival (CSS) in elderly patients with early-stage non-small cell lung cancer (NSCLC), and to find the best characteristics of the beneficiary population. Materials & methods: Based on the Surveillance, Epidemiology, and End Results (SEER) database, the effect of LND on OS and CSS in elderly patients with early-stage NSCLC was analyzed using a retrospective method. Multivariate Cox regression model was employed to determine the factors influencing OS and CSS in elderly patients with early-stage NSCLC. Kaplan-Meier and sequential landmark analyses were conducted to estimate and compare the survival curves and median follow-up time of patients. R

SUBMITTER: Zhang DC 

PROVIDER: S-EPMC12711093 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature