Global, regional, and national burden of autoimmune disease in older adults (≥60 years) from 1990 to 2021: Results from the Global Burden of Disease Study 2021.

ABSTRACT:

Objectives

To analyze and model the global, regional, and national burden of autoimmune diseases (ADs) among older adults (≥60 years) from 1990 to 2021.

Methods

Data were extracted from the Global Burden of Disease (GBD) 2021 data for 204 countries and territories. Age-standardized incidence, prevalence, mortality, and disability-adjusted life years (DALY) rates were calculated with 95% uncertainty intervals (UIs). Temporal trends were assessed using estimated annual percentage change (EAPC, with 95% Confidence Intervals [95% CI]). Future trends to 2035 were projected using a log-linear age-period-cohort model.

Results

In 2021, the Americas and Europe had the highest burden of ADs in older adults. From 1990 to 2021, age-standardized incidence and prevalence rates incr

SUBMITTER: Zeng SQ 

PROVIDER: S-EPMC12711659 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature