Epidemiological trends and determinants of mumps outbreaks: a systematic review and meta-analysis.

ABSTRACT:

Background

Despite widespread vaccination programs, mumps has resurged globally. This systematic review and meta-analysis assessed the epidemiological characteristics, attack rates (ARs), and complications of mumps outbreaks worldwide from 2004 to 2024.

Methods

We systematically searched MEDLINE, Embase, CINAHL and Google Scholar for studies reporting on mumps outbreaks. Confirmed mumps cases, defined by WHO criteria, were included across all age groups. Epidemiological characteristics were summarized using the Time-Place-Person format. Pooled ARs and complication rates were calculated using random-effects models. Subgroup analyses examined variations by age, region, vaccination status, and outbreak period. A random-effects meta-regression and leave one out sensitivity analy

SUBMITTER: Agrawal R 

PROVIDER: S-EPMC12711706 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature