Immunomodulatory, antioxidant, and growth-promoting properties of Avicennia marina leaf extract on Nile tilapia.

ABSTRACT: This study evaluated the effects of Avicennia marina leaf aqueous extract on Nile tilapia performance. Fish (5.15 g, n = 675) were fed diets containing 0, 100, 200, 300, and 400 mg/kg extract for 60 days. Fish fed 200-300 mg/kg diets showed better growth status (P < 0.05), along with improved feed utilization. Digestive enzyme levels (amylase, lipase, protease) were better, and intestinal histomorphology was optimized, particularly at 200-300 mg/kg. Biochemical assessment of the serum indicated increased levels of total protein, albumin, and globulin, with reduced glucose, cholesterol, and cortisol in fish receiving 200-400 mg/kg. Hepatic antioxidants (SOD, CAT, GSH-Px) increased, while malondialdehyde (MDA) decreased. Immune responses (lysozyme, NBT reduction, Streptococcus agalactiae inh

SUBMITTER: El Basuini MF 

PROVIDER: S-EPMC12711881 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature