Psychological and Related Factors Influencing Adherence to Biologic Therapies in Asthma: A Scoping Review.

ABSTRACT:

Purpose of review

This scoping review aimed to explore psychological and related biopsychosocial factors influencing adherence to biologic therapies among individuals with asthma. Despite the proven efficacy of biologics for severe type 2 inflammation, real-world adherence remains variable. The review sought to identify individual, clinical, and contextual determinants that facilitate or hinder adherence behaviors.

Recent findings

A systematic search of PubMed, Scopus, and APA PsycINFO identified 14 studies published between 2018 and 2025. Most were observational or retrospective and conducted in the United States. Adherence rates were generally moderate to high but varied across biologics. Systemic barriers included high out-of-pocket costs, complex insurance procedures, an

SUBMITTER: Poletti V 

PROVIDER: S-EPMC12711935 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature