Innovative essential oil formulations for in vitro inhibition of Biofilm-Forming Extended-Spectrum β-Lactamase-Producing Escherichia coli isolated from canine infectious diarrhea.

ABSTRACT:

Background

The emergence of bacteria producing extended-spectrum β-lactamases (ESBLs) has presented a substantial challenge to veterinary and human medicine. ESBL-producing Escherichia coli exhibits biofilm-forming capabilities that enhance its persistence in domestic animals, contribute to chronic infectious diarrhea, and increase the risk of treatment failure. This study investigated ESBL-producing E. coli in dogs and evaluated the antimicrobial and antibiofilm activities of NHK-EO, an innovative essential oil formulation derived from Coleus amboinicus (N), Ocimum basilicum (H), and Ocimum tenuiflorum (K).

Methods

The chemical composition of NHK-EO was analyzed using gas chromatography-mass spectrometry (GC-MS). Fifty-six rectal swab samples were randomly collected from do

SUBMITTER: Thongjuy O 

PROVIDER: S-EPMC12711979 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature