24-h urine test application in patients with kidney stone disease: a population-based study in a primary care setting.

ABSTRACT:

Background

Kidney stone formation is driven by an imbalance between lithogenic substances and crystallization inhibitors. Current guidelines recommend a 24-h urine collection in patients with kidney stone disease to assess the risk of stone formation and monitor therapy compliance. However, real-world data on adherence to these guidelines remain limited and outdated.

Methods

We used the Health Search Database to examine laboratory test data of patients with kidney stone disease between 2013 and 2022 in Italy. Adults with at least one episode of kidney or ureteral stones during this period were included. We used the prescription of urinary calcium, oxalate, and citrate levels as a proxy for full metabolic testing.

Results

A total of 21,907 adult patients were identifie

SUBMITTER: Ferraro PM 

PROVIDER: S-EPMC12711989 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature