Diagnostic accuracy of multiparametric MRI for detecting unconventional prostate cancer histology: a systematic review and meta-analysis.

ABSTRACT:

Background and objective

Accurate detection of unconventional histologies (UH) in prostate cancer (PCa) is crucial for treatment planning and prognosis. This systematic review and meta-analysis aimed to evaluate the accuracy of multiparametric magnetic resonance imaging (mpMRI) in detecting UH on prostatectomy, particularly cribriform architecture (CA) and intraductal carcinoma (IDC-P), in patients with localized PCa.

Methods

A literature search was conducted in major databases for studies published after 2000. Seventeen articles fulfilled the inclusion criteria and were eligible for qualitative analysis. Five studies met the inclusion criteria for meta-analysis.

Results

The pooled sensitivity and specificity of mpMRI (Prostate Imaging Reporting and Data System (PI-RA

SUBMITTER: Carletti F 

PROVIDER: S-EPMC12712012 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature