Longitudinal associations between iron status and patient-reported outcomes in incident dialysis patients: a DOMESTICO substudy.

ABSTRACT:

Background

More liberal use of iron therapy is favored in dialysis patients based on lower erythropoietin need and clinical outcomes. However, it remains unclear whether higher iron stores are associated with better patient-reported outcomes. We assessed the longitudinal associations of ferritin and transferrin saturation (TSAT) levels with patient-reported outcomes in incident dialysis patients.

Methods

This prospective cohort study included incident dialysis patients who had completed at least one patient-reported outcome questionnaire and had undergone a laboratory assessment (e.g., ferritin, transferrin saturation, hemoglobin) within the first year of dialysis. The primary outcome was health-related quality of life (HRQoL), measured using the 12-Item Short Form (SF-12) s

SUBMITTER: Mahic O 

PROVIDER: S-EPMC12712045 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature