Image quality in ultra-low-dose chest CT versus chest x-rays guiding paediatric cystic fibrosis care.

ABSTRACT:

Objectives

Cystic fibrosis (CF) is a prevalent autosomal recessive disorder, with lung complications being the primary cause of morbidity and mortality. In paediatric patients, structural lung changes begin early, necessitating prompt detection to guide treatment and delay disease progression. This study evaluates ultra-low-dose CT (ULDCT) versus chest x-rays  (CXR) for children with CF (CwCF) lung disease assessment. ULDCT uses AI-enhanced deep-learning iterative reconstruction to achieve radiation doses comparable to a CXR.

Materials and methods

This prospective study recruited radiographers and radiologists to assess the image quality (IQ) of ten paired ULDCT and CXR images of CwCF from a single centre. Statistical analyses, including the Wilcoxon Signed Rank test and vis

SUBMITTER: Moore N 

PROVIDER: S-EPMC12712111 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature