Adjunctive value of 3D MRCP in biliary atresia: a retrospective two-center analysis of cholestatic infants.

ABSTRACT:

Objectives

To evaluate the adjunctive diagnostic value of three-dimensional MR cholangiopancreatography (3D MRCP) for identifying biliary atresia (BA) in infants with cholestasis.

Materials and methods

This retrospective two-center study evaluated the adjunctive diagnostic performance of 3D MRCP beyond ultrasound (US) using receiver operating characteristic (ROC) analysis. The cohort from center 1 was divided into training (n = 770) and validation (n = 330) sets, with center 2 as the test set (n = 252). The optimal cut-off for the MR triangular cord thickness (MR-TCT) was derived from the area under the ROC curve (AUC) calculated from all cases. Extrahepatic bile ducts visualization on 3D MRCP was validated against surgical findings. Image quality metrics were assessed for t

SUBMITTER: Liu S 

PROVIDER: S-EPMC12712274 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature