What Is the Diagnostic Capacity of Existing Severity Scoring Tools for Nail Psoriasis?

ABSTRACT:

Background

It is challenging to distinguish nail psoriasis (NP) from nonspecific nail changes, contributing to heterogeneity in clinical trials. Existing scoring tools for NP are currently used to assess severity after diagnosis is established. The aim of this study is to evaluate the diagnostic performance of two of these severity scoring tools.

Methods

A cohort study was conducted with psoriasis patients and matched controls. Fingernails were scored using the Nail Psoriasis Severity Index (NAPSI) and the Nijmegen-Nail Psoriasis Activity Index Tool (N-NAIL). To determine their diagnostic properties, cutoff values were established. Receiver operating characteristic (ROC) curves were constructed, and sensitivity and specificity were calculated for various cutoff points. The b

SUBMITTER: Rikken ECC 

PROVIDER: S-EPMC12712757 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature