A Systematic Review of the Prognostic Value of Cardiopulmonary Exercise Testing in Patients with Ischemic and Nonischemic Cardiomyopathy.

ABSTRACT:

Background

The prognostic utility of cardiopulmonary exercise testing (CPET) in heart failure (HF) is well established; however, whether optimal CPET parameter thresholds differ across HF etiologies remains unclear. This systematic review aimed to determine how CPET-derived parameters and their prognostic threshold values differ, and their association with adverse outcomes, in patients with ischemic vs nonischemic cardiomyopathy.

Methods

Eligible studies assessed adult HF patients and reported outcomes of all-cause mortality, left ventricular assist device implantation, heart transplantation, or hospitalization. CPET parameters and associated threshold values were extracted, and risk of bias was assessed using the Joanna Briggs Institute checklist for cohort studies.

Resu

SUBMITTER: Lowes H 

PROVIDER: S-EPMC12713171 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature