Accelerated molecular aging in socioeconomically disadvantaged neighborhoods: A racial/ethnic comparison.

ABSTRACT: In the US, racial/ethnic health disparities are undeniable. These disparities partially stem from residing in low socioeconomic neighborhoods, a circumstance to which racial/ethnic minorities are disproportionately exposed. Associations between socioeconomic status (SES) and health may have some underlying molecular mechanisms reflected in the epigenome. Yet, a growing body of research suggests that neighborhood characteristics are not experienced the same way for individuals from differing racial/ethnic backgrounds. The present study evaluated associations between area-based SES and epigenetic age as assessed by the Horvath, Hannum, PhenoAge, and GrimAge epigenetic clocks in a national sample of older non-Hispanic White, non-Hispanic Black, and Hispanic participants. The present study use

SUBMITTER: Robinette JW 

PROVIDER: S-EPMC12713560 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature