Monitoring Vaccine-Induced Antibody Levels Using Carbon Nanotube-Based Field-Effect Transistors.

ABSTRACT: Vaccines are powerful public health tools to protect against emerging infectious pathogens. Multiple vaccine doses are typically required to achieve robust protection that is often mediated by the induction of pathogen-specific antibodies. Thus, monitoring the levels of vaccine-induced antibodies in immunized individuals is crucial to ensuring vaccine effectiveness and compliance. However, existing antibody-detection techniques are resource- and time-inefficient, highlighting the need for improved technologies for monitoring vaccine-induced antibody levels. Here, we developed a field-effect transistor (FET) biosensor platform based on antigen-functionalized semiconducting single-walled carbon nanotubes (SWCNTs) for the rapid and convenient detection of pathogen-specific antibodies. Our ant

SUBMITTER: Amiri A 

PROVIDER: S-EPMC12713613 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature