An integrated wearable fluorescence sensor for E. coli detection in catheter bags.

ABSTRACT: Urinary tract infections (UTIs), including catheter-associated UTIs (CAUTIs), affect millions worldwide. Traditional diagnostic methods, like urinalysis and urine culture, have limitations-urinalysis is fast but lacks sensitivity, while urine culture is accurate but takes up to two days. Here, we present an integrated wearable fluorescence sensor to detect UTI-related bacterial infections early at the point of care by on-body monitoring. The sensor features a hardware platform with a flexible PCB that attaches to a urine catheter bag, emitting excitation light and detecting emission light of E. coli-specific enzymatic reaction for continuous monitoring. Our custom-developed smartphone application allows remote control and data transfer via Bluetooth and performs in situ data analysis witho

SUBMITTER: Xu W 

PROVIDER: S-EPMC12714006 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature