Manipulation and Analysis of Cell Cycle-Dependent Processes in Budding Yeast.

ABSTRACT: Eukaryotic cells follow a conserved cell cycle that regulates diverse processes, including DNA maintenance and organelle homeostasis. Studying cellular processes in a cell cycle-dependent manner is often necessary to properly interpret experimental results. There are chemical and genetic methods available to produce cell cycle synchronization in cultured cells across a wide swath of organisms, including vertebrate models, enabling the study of cell cycle-dependent processes. However, among model organisms, budding yeast remains a powerhouse for cell cycle analysis due to its particularly robust synchronization methods, short generation time, and genetic tractability. Yeast shares core cell cycle machinery with other eukaryotes, which has enabled landmark discoveries in cell cycle regulatio

SUBMITTER: Stewart MG 

PROVIDER: S-EPMC12714067 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature