Effect of creep-feeding supplementation during the pre-weaning phase on gene co-expression in Longissimus thoracis muscle of F1 Angus x Nellore calves at weaning.

ABSTRACT: The aim of this study was to analyze gene co-expression in skeletal muscle of calves with or without creep-feeding during the pre-weaning phase. Forty-eight F1 uncastrated male Angus-Nellore calves were divided into two groups: G1 - no creep-feeding, and G2 - creep-feeding. After weaning (210 days), all animals were kept in the feedlot for 180 days under the same conditions. Weaning weight, backfat thickness, and intramuscular fat content were significantly higher in G2, with intramuscular fat and marbling score being 17.2% and 14.0% higher, respectively, compared with G1 (P < 0.05). Longissimus thoracis muscle samples were collected at weaning for transcriptome analysis (RNA-Seq) in 12 animals of each group. Gene co-expression analysis using the CEMiTool R package identified seven modules

SUBMITTER: Reolon HG 

PROVIDER: S-EPMC12714228 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature