Field evaluation of a dual treponemal/non-treponemal point-of-care test for syphilis within an HIV pre-exposure prophylaxis programme in Hanoi, Vietnam.

ABSTRACT:

Objectives

Syphilis infections are high among men who have sex with men (MSM) on HIV pre-exposure prophylaxis (PrEP). Point-of-care (POC) testing may improve diagnosis and treatment. We performed a field evaluation of the Chembio dual path platform (DPP) Syphilis Screen and Confirm treponemal/non-treponemal POC test within an HIV PrEP programme in Hanoi, Vietnam.

Methods

From December 2023 to July 2024, males aged ≥16 years enrolled in the HIV PrEP programme who reported sex with men in the last year were enrolled. Specimens were tested using the Chembio DPP syphilis screen and confirm test and reference treponemal (Abbott Bioline or Determine) and non-treponemal (rapid plasma reagin (RPR)) tests. Positive per cent agreement (PPA), negative per cent agreement (NPA), positive

SUBMITTER: Biba U 

PROVIDER: S-EPMC12714314 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature