Uptitration of statin therapy in women and men: a population-based cohort study.

ABSTRACT:

Aims

Statins are widely used for the prevention and management of cardiovascular disease (CVD). Women have been shown to be less likely to receive guideline-recommended dose of statins and reach target lipid levels. This study aims to examine sex differences in titration patterns of statin therapy and in the attainment of cholesterol targets in a Dutch healthcare setting.

Methods and results

Data on statin dispensing was extracted from the PHARMO Data Network between 2011 and 2020. New-statin users with at least two recorded statin dispenses were included. Cox proportional hazards models were used to study the association between sex and time to first uptitration of intensity and Poisson regressions were used to estimate sex differences in the attainment of cholesterol targe

SUBMITTER: Kiss P 

PROVIDER: S-EPMC12714376 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature