Adherence to perindopril/amlodipine/atorvastatin combination according to the administration strategy.

ABSTRACT:

Aims

To compare adherence to perindopril/amlodipine/atorvastatin combination administrated as a polypill (one pill) vs. separate tablets.

Methods and results

Using the healthcare utilization database of Lombardy (Italy), 1110 patients who received the perindopril/amlodipine/atorvastatin polypill during 2019-2021 were matched with 1110 patients prescribed the same combination in separate tablets or as two antihypertensive drugs in a single tablet and the lipid-lowering drug tablet separately. Adherence to treatment was assessed over the year after the first perindopril/amlodipine/atorvastatin dispensation as the proportion of the follow-up days covered by prescription (PDC). Patients with a PDC >75% and <25% were defined as highly and poorly adherent, respectively. Adherence

SUBMITTER: Morabito G 

PROVIDER: S-EPMC12714380 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature