Histologic patterns of chronic interstitial lung disease in dogs.

ABSTRACT: Chronic interstitial lung disease (cILD) is uncommon in dogs and little is known of the pathogenesis, apart from the condition in West Highland White Terriers. This study aimed to characterize histologic lesions of canine cILD, compare the lesions and clinical features, and classify the histopathologic patterns according to criteria used in humans. The study included 24 postmortem cases of subacute or chronic ILD in >6-month-old dogs with respiratory signs. Histologic lung lesions included attenuated bronchiolar epithelium, alveolar edema, type II pneumocyte proliferation, fibrosis of alveolar septa, fibrin or fibrous tissue within alveoli or bronchioles, and hyaline membranes. Of the 24 cases, 8 were classified as organizing diffuse alveolar damage, 4 as organizing pneumonia, and 3 as acu

SUBMITTER: Kozawa M 

PROVIDER: S-EPMC12714552 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature