Integrated metabolomic and transcriptomic analyses reveal temporal dynamics of secondary metabolite accumulation in <i>Cibotium barometz</i> rhizome.

ABSTRACT: Cibotium barometz (Gou-ji) is a valued traditional Chinese medicinal herb with demonstrated efficacy in treating musculoskeletal and age-related conditions. The pharmacological properties of Gou-ji are closely associated with its phytochemical composition. However, a systematic understanding of the metabolic profile and its temporal dynamics in the rhizome-the primary medicinal part-remains limited. This study aimed to comprehensively characterize the secondary metabolite composition of C. barometz rhizome and elucidate its developmental regulation. Our specific objectives were to: (1) compare the metabolomic profiles of rhizomes at juvenile (YDS), intermediate (MDS), and mature (MS) stages; (2) investigate the transcriptomic basis underlying metabolite accumula

SUBMITTER: Wang FP 

PROVIDER: S-EPMC12714926 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature