Long-term outcomes according to absolute value vs. percentage reduction in low-density lipoprotein cholesterol levels after acute myocardial infarction.

ABSTRACT:

Backgrounds/aims

Real-world data are limited regarding long-term outcomes in terms of absolute follow-up values of low-density lipoprotein cholesterol (LDL-C) vs. percentage reductions from baseline after LDL-C-lowering therapy for patients with acute coronary syndrome. We aimed to investigate the associations between 5-year clinical outcomes and absolute follow-up LDL-C levels or percentage reductions from baseline using a nationwide Korea Acute Myocardial Infarction Registry (KAMIR).

Methods

Of 13,662 patients from the KAMIR-National Institutes of Health database, we identified 6,248 patients who had documented LDL-C levels at baseline and during 18 months of follow-up. The primary outcome was major adverse cardiovascular events (MACE; a composite of nonfatal stroke, nonfa

SUBMITTER: Cho KH 

PROVIDER: S-EPMC12714945 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature