Global, regional, and national trends for childhood myocarditis from 1990 to 2021: health inequality and age-period-cohort analysis for the Global Burden of Disease Study 2021.

ABSTRACT:

Background

Childhood myocarditis (CM) may have a profound impact on lifelong health worldwide. This study aimed to assess the trends and explore the health inequality along with age-period-cohort (APC) analysis for CM from 1990 to 2021.

Methods

This study is based on the database for Global Burden of Disease (GBD) 2021. The age-standardized rate (ASR) of incidence, prevalence, mortality, and disability-adjusted life years (DALYs) was used to assess CM burden. Estimated annual percentage changes (EAPC) in ASR from 1990 to 2021 were used to calculate the time trends. Health inequalities related to the sociodemographic index (SDI) and APC effect for CM burden were studied in this study.

Findings

A significant decreasing trend for ASR of incidence, prevalence, mortality,

SUBMITTER: Fang HJ 

PROVIDER: S-EPMC12714953 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature