Impact of Craniocaudal Tumor Dimension and the Ninth Edition of the TNM Stage Classification on Prognosis in Resected Thymoma.

ABSTRACT:

Background

Thymoma is a rare thymic epithelial tumor, and its prognostic factors remain not fully elucidated. This study aimed to identify simple, practical preoperative predictors of prognosis, focusing on tumor dimensions assessed by computed tomography (CT).

Methods

We retrospectively analyzed 181 patients who underwent complete or partial resection for thymoma between 2004 and 2022. Tumor size was assessed by measuring the maximum transverse and craniocaudal dimensions on preoperative CT. Freedom from recurrence (FFR) and overall survival (OS) were estimated using the Kaplan-Meier method. Cox proportional hazards models were constructed: Model A included only preoperative variables, while Model B additionally incorporated postoperative factors (e.g., TNM stage classifica

SUBMITTER: Okazaki D 

PROVIDER: S-EPMC12715270 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature