Longitudinal Study of Treatment Variability for Parkinson's Disease across Specialized Centers.

ABSTRACT:

Background

Real-world evidence on treatment practices in Parkinson's disease (PD) has been limited due to the difficulty in collecting comprehensive and generalizable clinical data.

Objectives

We sought to identify treatment patterns and test how treatment changed in response to (1) falling, (2) worsening disease, and (3) worsening quality of life across PD specialized centers.

Methods

We used the Parkinson Outcomes Project data collected from 2010 to 2023 across 31 international PD specialized centers. Demographic and clinical characteristics were collected annually and included medication use, physical therapy referral, psychologist or psychiatrist care, and deep brain stimulation (DBS) surgery. Treatment practice variation was described by center and in response to

SUBMITTER: Dahodwala N 

PROVIDER: S-EPMC12715345 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature