Associations of Chronic Hepatitis B and Nonalcoholic Fatty Liver Diseases with New-Onset Metabolic Syndrome in Military Personnel before Midlife: A Cohort Study.

ABSTRACT:

Background

Hepatic inflammation, e.g., Nonalcoholic Fatty Liver Diseases (NAFLD) and the severe form of steatohepatitis (NASH), has been associated with a higher risk of MetS in the general population.

Aims

This study aimed to investigate the associations of chronic hepatitis B (CHB) and fatty liver diseases with the incidence of metabolic syndrome (MetS) in young adults, which have not been verified before.

Objective

The associations between NAFLD, NASH, and CHB and the incidence of new-onset MetS remain inconclusive in young adults.

Methods

This cohort study included 2,614 military personnel aged 18-39 years who were free of baseline MetS in 2014 and were followed for the incidence of MetS in each annual health examination until the end of 2020. CHB was defin

SUBMITTER: Tsai KZ 

PROVIDER: S-EPMC12715392 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature