Online Clinical Calculator for Predicting 28-Day Mortality in Older Adult Patients With Sepsis-Associated Encephalopathy: Retrospective Study Using MIMIC-IV.

ABSTRACT:

Background

Sepsis-associated encephalopathy (SAE) represents a critical complication of sepsis, especially among older adults. Despite its clinical relevance, there remains a lack of accessible and practical tools specifically designed to predict 28-day mortality in this vulnerable population.

Objective

We aimed to enhance the practical applicability of the model by creating a web-based tool that allows real-time, individualized mortality risk prediction, facilitating early intervention and informed decision-making in clinical practice.

Methods

Using data extracted from the MIMIC-IV (Medical Information Mart for Intensive Care IV) database, we identified older patients (≥65 years) with SAE (n=2165) and divided them into a development cohort (n=1531) and a validation c

SUBMITTER: Jin G 

PROVIDER: S-EPMC12715468 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature